
EPISODE 116: GIVEN 5 YEARS TO LIVE—HERE’S HOW SHE BIOHACKED AUTOIMMUNITY AND AGING with Leslie Kenny
Jun 19, 2025Given 5 Years to Live—Here’s How She Biohacked Autoimmunity and Aging
The 60-Year-Old with the Body of a 21-Year-Old
The Woman Who Turned a Death Sentence Into a Longevity Breakthrough
What if your biological age could be decades younger than your actual one? At nearly 60, Leslie Kenny has the cellular health of a 21-year-old, and in this riveting conversation, she shares exactly how she did it. From battling multiple autoimmune diseases and being given five years to live, to becoming a global leader in the longevity space, Leslie’s transformation is nothing short of miraculous. In this episode, she unpacks the science behind bioidentical hormone therapy, the power of spermidine and autophagy, and the critical role of personalized, anti-inflammatory living. You’ll also hear her honest experiences with thyroid health, fertility, and why advocating for your own wellbeing is non-negotiable. Whether you're 35 or 75, this is your invitation to rewrite your health destiny and thrive in your second half of life.
KEY TAKEAWAYS:
- How can women reverse biological aging through hormone therapy, nutrition, and lifestyle choices?
- What role does spermidine and immune system resetting play in achieving long-term vitality and health?
- Why is self-advocacy essential when navigating autoimmune conditions and finding the right healthcare support?
AUDIO KEY TIMESTAMPS:
(00:00) - Longevity, immune resetting, and mindset shifts
(03:00) - Leslie’s transformation from illness to vitality
(06:00) - The new narrative around aging for women
(08:00) - Hormone therapy: BHRT and its impact
(14:00) - DHEA, pregnenolone, and self-advocacy in care
(18:00) - Thyroid health and overlooked symptoms
(25:00) - Investing in the right healthcare support
(27:00) - Spermidine, Primeadine, and autophagy explained
(51:00) - IVIG and immune system reset
VIDEO KEY TIMESTAMPS:
(00:00) - The rebellious nature of boomers and their longevity
(04:00) - Leslie’s transformation story and biological age of 21
(06:00) - Understanding BHRT and breast cancer concerns
(08:00) - DHEA experiences and risks of self-dosing
(10:00) - Progesterone, DHEA, and practitioner insights
(16:00) - Thyroid health, symptoms, and misdiagnosis
(19:00) - T3, reverse T3, and metabolic slowdown
(23:00) - Health investments and patient-doctor relationships
(27:00) - Recipes and creative ways to take primeadine
(34:00) - Spermidine’s impact on mitochondria and synergy with food
(48:00) - Sleep optimization tools and routines
(52:00) - IVIG and alternative protocols
MENTIONS:
Website: https://oxfordhealthspan.com/
Instagram: https://www.instagram.com/lesliesnewprime/?hl=en
Mentions: Intravenous Immunoglobulin (IVIG)
KEY TOPICS DISCUSSED:
WELLPOWER, Kristin Weitzel, biohacking, health and wellness, women’s health, cold exposure, breathwork, scientific research, heat optimization, reverse biological age, Spermidine supplement benefits, Bioidentical hormone therapy for women, Autoimmune disease recovery, Longevity and anti-aging strategies
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Website: https://www.wellpower.life/
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